AXL antibody (10R-2051)

Mouse monoclonal AXL antibody

Synonyms Monoclonal AXL antibody, Anti-AXL antibody, AXL receptor tyrosine kinase antibody, JTK11 antibody, UFO antibody
Cross Reactivity Human
Applications ELISA, IF, WB
Immunogen AXL antibody was raised in Mouse using purified recombinant extracellular fragment of human AXL fused with hIgGFc tag expressed in HEK293 cell line as the immunogen.

Images

Immunofluorescent staining using Western Blot analysis using AXL antibody (10R-2051) (AXL antibody)

Confocal immunofluorescence analysis of methanol-fixed HEK293 cells trasfected with AXL-hIgGFc using AXL antibody (green), showing cytoplasmic and membrane localization. Blue: DRAQ5 fluorescent DNA dye.

Specifications

Host Mouse
Clone 7E10
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IF: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance AXL is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

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Images

  • Immunofluorescent staining using Western Blot analysis using AXL antibody (10R-2051) (AXL antibody) | Confocal immunofluorescence analysis of methanol-fixed HEK293 cells trasfected with AXL-hIgGFc using AXL antibody (green), showing cytoplasmic and membrane localization. Blue: DRAQ5 fluorescent DNA dye.
  • Western Blot analysis using AXL antibody (10R-2051) | Western Blot showing AXL antibody used against extracellular domain of human AXL (aa19-444).

Availability: In stock

Price: $345.00
Size: 100 ul
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