BAK1 antibody (70R-10449)
Affinity purified rabbit polyclonal BAK1 antibody
|Synonyms||Polyclonal BAK1 antibody, Anti-BAK1 antibody, BAK antibody, BCL2L7 antibody, BAK-LIKE antibody, BAK 1 antibody, MGC117255 antibody, MGC3887 antibody, BAK1, CDN1 antibody, BAK-1 antibody, BAK 1, BCL2-antagonist/killer 1 antibody, BAK-1|
|Immunogen||BAK1 antibody was raised in rabbit using the N terminal of BAK1 as the immunogen|
|Assay Information||BAK1 Blocking Peptide, catalog no. 33R-1505, is also available for use as a blocking control in assays to test for specificity of this BAK1 antibody|
Western Blot analysis using BAK1 antibody (70R-10449)
BAK1 antibody (70R-10449) used at 0.2-1 ug/ml to detect target protein.
|Form & Buffer||Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.|
Usage & Assay Information
|Usage Recommendations||WB: 0.2-1 ug/ml|
Storage & Safety
|Storage||Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.|
|Biological Significance||BAK1 belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.|
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