BCL10 protein (His tag) (80R-2200)
Purified recombinant Human BCL10 Protein (His tag)
|Synonyms||BCL-10, CARMEN protein, c-E10 protein, BCL 10 protein, CIPER protein, BCL-10 protein, B-cell lymphoma/leukemia 10 protein, CLAP protein, mE10 protein, BCL10, BCL 10|
Coomassie Blue stained SDS-PAGE of BCL10 protein (His tag) (80R-2200)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||MGSSHHHHHH SSGLVPRGSH MGSHMEPTAP SLTEEDLTEV KKDALENLRV YLCEKIIAER HFDHLRAKKI LSREDTEEIS CRTSSRKRAG KLLDYLQENP KGLDTLVESI RREKTQNFLI QKITDEVLKL RNIKLEHLKG LKCSSCEPFP DGATNNLSRS NSDESNFSEK LRASTVMYHP EGESSTTPFF STNSSLNLPV LEVGRTENTI FSSTTLPRPG DPGAPPLPPD LQLEEEGTCA NSSEMFLPLR SRTVSRQ|
|Purity||> 85% pure|
|Molecular Weight||28.8 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol, 0.05M NaCl, 1mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||BCL10 contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma.|
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