Bcl2 antibody (20R-2960)

Rabbit polyclonal Bcl2 antibody

Synonyms Polyclonal Bcl2 antibody, Anti-Bcl2 antibody, BCL2 antibody, B-cell CLL/lymphoma 2 antibody, apoptosis regulator Bcl-2 antibody, apoptosis regulator Bcl-2 protein antibody, B cell leukemia/lymphoma 2 antibody, B-cell leukemia/lymphoma 2 antibody, B cell lymphoma 2 associated oncogene antibody, B-cell lymphoma protein 2 antibody, Bcl-2 antibody, BCL2B-cell CLL/lymphoma 2 antibody, Bcl2-like protein antibody, BOS_22233 antibody, mitochondrial B-cell CLL/lymphoma 2 antibody, PCKBCL2 antibody, PPP1R50 antibody, protein phosphatase 1 antibody, regulatory subunit 50 antibody, xbcl2 antibody, xBcl-2 antibody, zBlp2 antibody
Cross Reactivity Human
Applications WB
Immunogen Bcl2 antibody was raised in Rabbit using a recombinant human protein purified from E.coli(His-Bcl-2 1-211 a.a.) as the immunogen

Images

Western Blot analysis using Bcl2 antibody (20R-2960)

Specifications

Host Rabbit
Isotype IgG
Method of Purification Bcl2 antibody was purified by Protein A affinity chromatography
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:2000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance The Bcl2 gene has been implicated in a number of cancers, including melanoma, breast, prostate, and lung carcinomas, as well as schizophrenia and autoimmunity. It is also thought to be involved in resistance to conventional cancer treatment. Apoptosis is an important component of the sequence of events during which anticancer drugs induce an antitumor response. The molecular mechanism for drug-induced apoptosis is associated with a mitochondrial dysfunction that is characterized by an increase in MOMP and a release of cytochrome c from mitochondria, indicating that Bcl-2 plays a critical role in anticancer drug-induced apoptosis.

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Images

  • Western Blot analysis using Bcl2 antibody (20R-2960) |

Availability: In stock

Price: $295.00
Size: 100 ul
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