BCL2L2 protein (His tag) (80R-1239)
Purified recombinant Human BCL2L2 protein
|Synonyms||BCL2 like 2 protein, KIAA0271., BCLL 2, BCLL-2 protein, Bcl 2 like 2 protein protein, BCL2 like 2 protein protein, BCL2L2, Apoptosis regulator Bcl-W protein, BCLL-2, Bcl 2L2 protein, bcl w protein, BCLL 2 protein, Bcl2 L2 protein, BCL2-like protein 2 Apoptosis regulator BCL W protein, BCL 2 Like 2 protein, BCLW protein|
Coomassie Blue stained SDS-PAGE of BCL2L2 protein (His tag) (80R-1239)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-172 amino acids: MGSSHHHHHH SSGLVPRGSH MATPASAPDT RALVADFVGY KLRQKGYVCG AGPGEGPAAD PLHQAMRAAG DEFETRFRRT FSDLAAQLHV TPGSAQQRFT QVSDELFQGG PNWGRLVAFF VFGAALCAES VNKEMEPLVG QVQEWMVAYL ETRLADWIHS SGGWAEFTAL YGDGALEEAR RLREGNWASV RT|
|Purity||> 95% pure|
|Molecular Weight||20.9 kDa (192aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 7.5, containing 100mM NaCl and 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||BCL2-like protein 2, also known as BCL2L2, is a member of the Bcl-2 family of proteins that regulates outer mitochondrial membrane permeability. BCL2L2 is an anti apoptotic member that prevents release of cytochrome c from the mitochondria intermembrane space into the cytosol. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. It is required for normal sperm maturation. Recombinant human BCL2L2, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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