BD2 protein (30R-AB005)

Purified recombinant Human BD2 protein

Synonyms BD-2, BD 2 protein, BD-2 protein, SAP1 protein, BD2, Skin-antimicrobial peptide 1 protein, BD 2 protein, BD 2, BD-2 protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of BD2 protein corresponding to amino acids GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P.
Expression System E.coli
Purity > 98% pure
Molecular Weight 4.3 kDa
Form & Buffer Supplied lyophilized with no additives. Reconstitute in 10 mM Acetic Acid to a concentration of 0.1 - 1.0 mg/ml.

Usage & Assay Information

Bioactivity Determined by its ability to chemoattract immature human dendritic cells using a concentration of 10.0-100.0 ng/ml.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells.

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Availability: In stock

Price: $225.00
Size: 20 ug
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