BD4 protein (30R-AB034)

Purified recombinant Human BD4 protein

Synonyms BEFB4 protein, BD 4 protein, beta-defensin 104 protein, BD 4 protein, BD-4, BD-4 protein, BD 4, BD4, BD-4 protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of BD4 protein corresponding to amino acids EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP.
Expression System E.coli
Purity > 98% pure
Molecular Weight 6.0 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity Determined by its ability to chemoattract human monocytes using a concentration range of 0.1-100.0 ng/ml.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. The beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence. beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. beta-defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues. BD-4 is expressed in testis, stomach, uterus, neutrophils, thyroid, lung and kidney.

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Availability: In stock

Price: $225.00
Size: 20 ug
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