BEX1 protein (His tag) (80R-2883)
Purified recombinant BEX1 protein (His tag)
|Synonyms||Brain expressed protein, X-linked 1 protein, BEX2 protein, HBEX2 protein, HGR74-h protein, BEX1, BEX 1, BEX-1, BEX1 protein, BEX 1 protein, BEX-1 protein|
SDS-PAGE analysis of BEX1 protein (His tag) (80R-2883)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-125 aa: MGSSHHHHHH SSGLVPRGSH MGSMESKEKR AVNSLSMENA NQENEEKEQV ANKGEPLALP LDAGEYCVPR GNRRRFRVRQ PILQYRWDMM HRLGEPQARM REENMERIGE EVRQLMEKLR EKQLSHSLRA VSTDPPHHDH HDEFCLMP|
|Purity||> 80% pure|
|Molecular Weight||17.2 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol|
Storage & Safety
|Storage||Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.|
|Biological Significance||Brain expressed, X-linked 1, also known as BEX1, is signaling adapter molecule involved in p75NTR/NGFR signaling. This protein plays a role in cell cycle progression and neuronal differentiation. This protein inhibits neuronal differentiation in response to nerve growth factor (NGF). It may act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states.|
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