BIRC7 antibody (70R-10452)

Affinity purified rabbit polyclonal BIRC7 antibody

Synonyms Polyclonal BIRC7 antibody, Anti-BIRC7 antibody, MLIAP antibody, BIRC 7, KIAP antibody, BIRC-7, livin antibody, RNF50 antibody, BIRC-7 antibody, BIRC7, ML-IAP antibody, LIVIN antibody, baculoviral IAP repeat-containing 7, BIRC 7 antibody
Cross Reactivity Human
Applications WB
Immunogen BIRC7 antibody was raised in rabbit using the middle region of BIRC7 as the immunogen
Assay Information BIRC7 Blocking Peptide, catalog no. 33R-2387, is also available for use as a blocking control in assays to test for specificity of this BIRC7 antibody

Images

Western Blot analysis using BIRC7 antibody (70R-10452)

Western Blot showing BIRC7 antibody used at a concentration of 1-2 ug/ml to detect its target protein.

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance BIRC7 protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits caspase-3 and proteolytic activation of pro-caspase-9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis.

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Images

  • Western Blot analysis using BIRC7 antibody (70R-10452) | Western Blot showing BIRC7 antibody used at a concentration of 1-2 ug/ml to detect its target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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