BMP2 protein (30R-2151)
Purified recombinant Human BMP2 Protein
|Synonyms||BMP-2, BMP 2, BMP-2A protein, BMP-2 protein, Bone morphogenetic protein 2, BMP2, BMP-2 protein, BMP 2 protein|
Coomassie Blue stained SDS-PAGE of BMP2 protein (30R-2151)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR|
|Purity||> 90% pure|
|Molecular Weight||13 kDa|
|Form & Buffer||Supplied in liquid form in 10 mM Sodium acetate (pH 3.5)|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1-2 weeks). Aliquot and store at -20 deg C to -70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||BMP2 is multi-functional growth factor that belongs to the transforming growth factor beta (TGF beta) superfamily. It plays an important role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility. Recombinant human BMP-2 protein was expressed in E.coli and purified by using conventional chromatography techniques, after refolding of the isolated inclusion body in renaturation buffer.|
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