BMP7 antibody (10R-B125A)

Mouse monoclonal BMP7 antibody

Synonyms Monoclonal BMP7 antibody, Anti-BMP7 antibody, BMP 7 antibody, BMP-7, BMP7, BMP-7 antibody, BMP 7, 7 antibody, Bone Morphogenetic antibody, BMP-7 antibody, OP-1 antibody
Specificity Human BMP7
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen BMP7 antibody was raised in mouse using recombinant human BMP-7/OP-1 as the immunogen.

Specifications

Host Mouse
Clone M912263
Isotype IgG1 kappa
Molecular Weight 28.8 kDa (predicted detection band MW)
Form & Buffer Lyophilized from PBS.

Usage & Assay Information

Usage Recommendations ELISA: 2-4 ug/ml

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance TGF beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-7, also known as osteogenic protein-1 or OP-1, is a potent bone inducing agent, which in the presence of appropriate osteoconductive carrier (e.g. collagen sponge or synthetic hydroxyapatite) can be used in the treatment of bone defects. A bone-graft substitute, called OP-1TM implant, made of recombinant human BMP-7 associated with bovine bone-derived collagen, has recently been approved by the FDA as a device for treating critical-size bone fractures.

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Availability: In stock

Price: $225.00
Size: 500 ug
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