BMP7 protein (30R-AB031)

Purified recombinant Human BMP7 protein

Synonyms BMP 7 protein, BMP7, Bone Morphogenetic protein 7 protein, BMP-7, BMP-7 protein, OP-1 protein, BMP 7, BMP-7 protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of BMP7 protein corresponding to amino acids MANVAENSSS DQRQACKKHE LYVSFRDLGW QDWIIAPEGY AAYYCEGECA FPLNSYMNAT NHAIVQTLVH FINPETVPKP CCAPTQLNAI SVLYFDDSSN VILKKYRNMV VRACGCH.
Expression System CHO cells
Purity > 98% pure
Molecular Weight 28.8 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.02-0.04 ug/ml.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance BMP-7, also known as osteogenic protein-1 or OP-1, is a potent bone inducing agent, which in the presence of appropriate osteoconductive carrier (e.g. collagen sponge or synthetic hydroxyapatite) can be used in the treatment of bone defects. A bone-graft substitute, called OP-1TM implant, made of recombinant human BMP-7 associated with bovine bone-derived collagen, has recently been approved by the FDA as a device for treating critical-size bone fractures.

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Availability: In stock

Price: $225.00
Size: 10 ug
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