BMX antibody (10R-2184)

Mouse monoclonal BMX antibody

Synonyms Monoclonal BMX antibody, Anti-BMX antibody, NTK38 antibody, Bone marrow X kinase antibody, PSCTK2 antibody, BMX non-receptor tyrosine kinase antibody, ETK antibody, NTK38 tyrosine kinase antibody
Cross Reactivity Hunam
Applications ELISA, WB
Immunogen BMX antibody was raised in Mouse using a purified recombinant fragment of human BMX expressed in E. coli as the immunogen.

Images

Western Blot analysis using BMX antibody (10R-2184)

Western Blot showing BMX antibody used against BMX (AA: 138-276)-hIgGFc transfected HEK293 cell lysate.

Specifications

Host Mouse
Clone 1C6
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, WB: 1:500-1:2000,

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance BMX is a cytoplasmic tyrosine kinase identified by reverse transcription of mRNA isolated from human bone marrow and mapped to the chromosomal band Xp22. 2. The full length protein is 675 amino acids with a tyrosine kinase domain, an amino terminal pleckstrin domain, as well as an SH3 and SH2 domain. Direct comparison of BMX's primary sequence with other kinases showed that this is highly related to the family of BTK/ITK/TEC. BMX kinase is expressed in fetal and adult tissues, with the highest expression in heart, testis, small intestine and colon. It is undetectable in spleen, brain, kidney, and pancreas. Further analysis of mRNA expression showed that BMX is expressed in hematopoietic tissues and neutrophilic granulocytes, and in patients with acute and myeloid leukemia.

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Images

  • Western Blot analysis using BMX antibody (10R-2184) | Western Blot showing BMX antibody used against BMX (AA: 138-276)-hIgGFc transfected HEK293 cell lysate.

Availability: In stock

Price: $345.00
Size: 100 ul
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