BTK antibody (10R-1929)

Mouse monoclonal BTK antibody

Synonyms Monoclonal BTK antibody, Anti-BTK antibody, Brutons tyrosine kinase antibody
Cross Reactivity Human, Monkey
Applications ELISA, IF, IHC, WB
Immunogen BTK antibody was raised in Mouse using a purified recombinant fragment of BTK expressed in E. coli as the immunogen.

Images

Immunofluorescent staining using Western Blot analysis using BTK antibody (10R-1929) (BTK antibody)

Immunofluorescence analysis of Jurkat cells using BTK antibody.

Specifications

Host Mouse
Clone 7F12H4
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance BTK is a member of the BTK/Tec family of cytoplasmic tyrosine kinases. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini. BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Immunofluorescent staining using Western Blot analysis using BTK antibody (10R-1929) (BTK antibody) | Immunofluorescence analysis of Jurkat cells using BTK antibody.
  • Western Blot analysis using BTK antibody (10R-1929) | Western Blot showing BTK antibody used against K562 (1), MCF-7 (2), Jurkat (3) and HEK293 (4) cell lysate.
  • Immunohistochemical staining using BTK antibody (10R-1929) | Immunohistochemical analysis of paraffin-embedded human lymph-node tissues (left) and human lymph follicle tissues (right), showing cytoplasmic and membrane localization using BTK antibody with DAB staining.

Availability: In stock

Price: $345.00
Size: 100 ul
OR
Shipping
View Our Distributors