C14orf169 antibody (10R-1463)

Mouse monoclonal C14orf169 antibody

Synonyms Monoclonal C14orf169 antibody, Anti-C14orf169 antibody, Corf169-14 antibody, Corf169 14 antibody, Corf169-14, FLJ21802 antibody, Corf169 14, Chromosome 14 open reading frame 169 antibody, C14orf169
Specificity Human C14orf169
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen C14orf169 antibody was raised in mouse using recombinant Human Chromosome 14 Open Reading Frame 169 (C14Orf169)

Images

Western Blot analysis of immunized recombinant protein using C14orf169 antibody (10R-1463)

Specifications

Host Mouse
Clone 3354C5a
Isotype IgG1
Method of Purification C14orf169 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer C14orf169 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance C14orf169 encodes a histone demethylase that specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys 36' (H3K36me2). It also acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity). May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region.

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Images

  • Western Blot analysis of immunized recombinant protein using C14orf169 antibody (10R-1463)

Availability: In stock

Price: $190.00
Size: 50 ug
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