C8G protein (His tag) (80R-1991)

Recombinant human C8G protein (His tag)

Synonyms C8C protein, CG 8, CG-8 protein, complement component 8 protein, gamma polypeptide protein, CG-8, CG 8 protein, C8G
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of C8G protein (His tag) (80R-1991)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 21-202 amino acids: MGSSHHHHHH SSGLVPRGSH MQKPQRPRRP ASPISTIQPK ANFDAQQFAG TWLLVAVGSA CRFLQEQGHR AEATTLHVAP QGTAMAVSTF RKLDGICWQV RQLYGDTGVL GRFLLQARGA RGAVHVVVAE TDYQSFAVLY LERAGQLSVK LYARSLPVSD SVLSGFEQRV QEAHLTEDQI FYFPKYGFCE AADQFHVLDE VRR
Expression System E.coli
Purity > 95% pure
Molecular Weight 22.6 kDa (203aa), confirmed by MALDI-TOF
Tag/Conjugate His tag
Form & Buffer Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.15M NaCl.
Concentration 0.5 mg/ml

Usage & Assay Information

Usage Recommendations C8G protein (His tag) has been used in SDS-PAGE, and may be suitable for use in other applications, to be determined by the end user.

Storage & Safety

Storage Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.

General Information

Biological Significance C8gamma, also known as C8G, is one of three polypeptides (along with C8 alpha and C8 beta) that constitutes C8, a component of the complement system. C8 participates in the formation of Membrane Attack Complex (MAC). Patients with deficiency in C8 are vulnerable to certain bacteria infection. C8gamma is a secreted protein that is able to bind retinol and belongs to the lipocalin family and calycin superfamily. It is synthesised in the liver, monocytes and fibroblast and functions to clear pathogens from an infected host. Recombinant human C8G protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of C8G protein (His tag) (80R-1991) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $270.00
Size: 100 ug
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