CA 15-3 antibody (10-CA15C)

Mouse monoclonal CA 15-3 antibody

Synonyms Monoclonal CA 15-3 antibody, Anti-CA 15-3 antibody, Cancer Antigen 15-3 antibody, CA 15-3, CA 15-3 antibody, CA15-3 antibody, CA15-3, Breast Tumor antibody
Cross Reactivity Minimal cross reactivity with Human CA125
Applications ELISA
Immunogen CA 15-3 antibody was raised in Mouse using Human CA 15-3 antigen from Human cell line as the immunogen
Assay Information 10-CA15C can be used as the capture antibody in a matched pair immunoassay inconjunction with 10-CA15B or 10-CA15BHRPas the detection antibody

Specifications

Host Mouse
Clone M59891
Isotype IgG2b
Method of Purification CA 15-3 antibody was purified by protein A chromatography
Form & Buffer Supplied in 0.015 M KP04 buffer, pH 7.4, containing 0.85% NaCl and 0.05% NaN3.

Storage & Safety

Storage Store at 2-8 deg C

General Information

Biological Significance CA 15-3 (also known as MUC1) is the most widely used serum marker in breast cancer. MUC1 is a large transmembrane glycoprotein which is frequently overexpressed and aberrantly glycosylated in cancer. Physiologically, MUC1 appears to play a role in cell adhesion and the high levels present in cancer may be causally involved in metastasis. At present the main uses of CA 15-3 are in preclinically detecting recurrent breast cancer and monitoring the treatment of patients with advanced breast cancer.

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CA 15-3 antibody

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Availability: In stock

Price: $495.00
Size: 1 mg
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