CA 19-9 protein (30-AC15S)
Partially purified Human CA 19-9 protein
Overview
Overview
| Synonyms | CA 19-9, CA19-9 protein, Gastrointestinal Tumor Antigen, Cancer Antigen 19-9 protein, CA19-9 |
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| Species | Human |
| Protein Type | Native |
| Applications | Control |
Specifications
| Source | Human ascites fluid |
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| Purity | Partially pure |
| Form & Buffer | Sterile filtered in PBS, pH 7.4, with 0.1% NaN3. |
| Concentration | 20,000-120,000 U/ml Roche Elecsys |
Usage & Assay Information
| Usage Recommendations | This partially pure product is usually used to make standards, calibrators and single analyte controls. |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Contaminants | It may contain various quantities of other tumor marker proteins such as Ca125, CEA, Ca 72.4, Cross-contaminates will vary from lot to lot due to the variability of the raw materials. |
| Biohazard Information | This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. All donor serum tested negative for HIV1, 2, HIVAg, HbsAg, HCV Ab and HCV Ag. |
General Information
| Biological Significance | Gastrointestinal tumor antigen is a large glycoprotein defined by a carbohydrate epitope, CA 19-9, located on a protein core mucin. It is referred to in the literature as sialylated Lewis A (Lea). It is over expressed by epithelial tumors of the gastro intestine including the stomach, small and large intestine, colon, pancreas and cervix. These mucins are largely carbohydrate, 80-90%. |
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