CA1 antibody (10R-1980)
Mouse monoclonal CA1 antibody
|Synonyms||Monoclonal CA1 antibody, Anti-CA1 antibody, Carbonic anhydrase B antibody, CAN antibody, yadF antibody, CAB antibody, JW0122 antibody, Carbonic anhydrase 1 antibody, Carbonic dehydratase antibody, Car 1 antibody, ECK0125 antibody, CA-I antibody, CAI antibody, Carbonate dehydratase I antibody, Car1 antibody|
|Immunogen||CA1 antibody was raised in Mouse using a purified recombinant fragment of CA1(aa25-90) expressed in E. coli as the immunogen.|
Western Blot analysis using CA1 antibody (10R-1980)
Western Blot showing CA1 antibody used against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY CA1 cDNA (2).
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.|
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