Carbonyl reductase 3 protein (His tag) (80R-1166)

Purified recombinant Human Carbonyl reductase 3 protein

Synonyms hCBR3 protein, NADPH-dependent carbonyl reductase protein, EC 1.1.1.184 protein, CBR3 protein, Carbonyl reductase (NADPH) 3 protein, Short chain dehydrogenase/reductase family 21C member 2., Carbonyl reductase (NADPH) 3 EC 1.1.1.184 protein, SDR21C2 protein, NADPH dependent carbonyl reductase 3 protein, Carbonyl reductase 3 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of Carbonyl reductase 3 protein (His tag) (80R-1166)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-277 amino acids: MGSSHHHHHH SSGLVPRGSH MSSCSRVALV TGANRGIGLA IARELCRQFS GDVVLTARDV ARGQAAVQQL QAEGLSPRFH QLDIDDLQSI RALRDFLRKE YGGLNVLVNN AAVAFKSDDP MPFDIKAEMT LKTNFFATRN MCNELLPIMK PHGRVVNISS LQCLRAFENC SEDLQERFHS ETLTEGDLVD LMKKFVEDTK NEVHEREGWP NSPYGVSKLG VTVLSRILAR RLDEKRKADR ILVNACCPGP VKTDMDGKDS IRTVEEGAET PVYLALLPPD ATEPQGQLVH DKVVQNW
Expression System E.coli
Purity > 95% pure
Molecular Weight 33 kDa (297aa), confirmed by MALDI-TOF.
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Carbonyl reductase 3(CBR3) is one of several monomeric NADPH-dependent oxidoreductases. This protein catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. It also contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene ? CBR1. Some studies suggest that it mediates 9-cis-retinoic acid-induced cytostatis and is a potential prognostic marker for oral malignancy. Recombinant human CBR3, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

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Images

  • Coomassie Blue stained SDS-PAGE of Carbonyl reductase 3 protein (His tag) (80R-1166) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $255.00
Size: 100 ug
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