Carboxypeptidase E antibody (10R-C115B)

Mouse monoclonal Carboxypeptidase E antibody

Synonyms Monoclonal Carboxypeptidase E antibody, Anti-Carboxypeptidase E antibody
Specificity Human CPE
Cross Reactivity To be determined by end-user
Applications ELISA, IP, WB
Immunogen Carboxypeptidase E antibody was raised in mouse using purified, NSO-derived, recombinant human CPE as the immunogen.

Specifications

Host Mouse
Clone 420709/M8100701
Isotype IgG2a
Form & Buffer Supplied lyophilized from a 0.2 um filtered solution in PBS, with 5% Trehalose. Reconstitute with sterile PBS. If 0.2 ml of PBS is used, the antibody concentration will be 0.5 mg/ml.

Usage & Assay Information

Usage Recommendations ELISA: 0.5-1.0 ug/ml, IP: 25 ug/ml, WB: 1-2 ug/ml

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Carboxypeptidase E (CPE) is a peripheral membrane protein that cleaves C-terminal amino acid residues and is involved in the processing of numerous peptide hormones and neurotransmitters. CPE knockout mice live but become obese due to impaired glucose clearance and insulin resistance. The CPE precursor includes a signal peptide (aa 1 - 25), a propeptide (aa 26 - 42) and a mature chain (aa 43 - 476). The amino acid sequence of human CPE is 99.8%, 96.6%, 96.3%, and 90.2% identical to that of chimpanzee, mouse, dog and chicken.

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Availability: In stock

Price: $395.00
Size: 100 ug
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