CARD18 protein (His tag) (80R-2203)
Purified recombinant Human CARD18 Protein (His tag)
|Synonyms||ICEBERG protein, CARD18, CARD 18, CARD-18 protein, UNQ5804 protein, CARD 18 protein, pseudo-ICE protein, CARD-18, Caspase recruitment domain-containing protein 18 protein|
Coomassie Blue stained SDS-PAGE of CARD18 protein (His tag) (80R-2203)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||MGSSHHHHHH SSGLVPRGSH MADQLLRKKR RIFIHSVGAG TINALLDCLL EDEVISQEDM NKVRDENDTV MDKARVLIDL VTGKGPKSCC KFIKHLCEED PQLASKMGLH|
|Purity||> 95% pure|
|Molecular Weight||12.3 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT,10% glycerol, 0.1M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||CARD18 inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B.|
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