CARHSP1 protein (His tag) (80R-1491)
Purified recombinant Human CARHSP1 protein
|Synonyms||CARHSP-1, CARHSP-1 protein, Calcium-regulated heat stable protein 1, CSDC1 protein, CARHSP 1 protein, CRHSP-24 protein, MGC111446 protein, CARHSP 1, CARHSP1|
Coomassie Blue stained SDS-PAGE of CARHSP1 protein (His tag) (80R-1491)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-147 amino acids: MGSSHHHHHH SSGLVPRGSH MSSEPPPPPQ PPTHQASVGL LDTPRSRERS PSPLRGNVVP SPLPTRRTRT FSATVRASQG PVYKGVCKCF CRSKGHGFIT PADGGPDIFL HISDVEGEYV PVEGDEVTYK MCSIPPKNEK LQAVEVVITH LAPGTKHETW SGHVISS|
|Purity||> 90% pure|
|Molecular Weight||18.0 kDa (167aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol and 0.1M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||CRAHSP1 is a serine phosphoprotein originally identified as a physiological substrate for the Ca2+-calmodulin regulated protein phosphatase calcineurin (PP2B). This protein interacts with the STYX/dead phosphate protein in developing spermatids and is a paralog of the brain-specific mRNA-binding protein PIPPIN. It is thought to play a common role in calcium-mediated signal transduction resulting from phosphorylation on serine residues. Recombinant human CRAHSP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques|
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