Caspase 2 antibody (20R-2898)

Rabbit polyclonal Caspase 2 antibody

Synonyms Polyclonal Caspase 2 antibody, Anti-Caspase 2 antibody, CASP2 antibody, caspase 2 antibody, apoptosis-related cysteine peptidase antibody, BOS_4782 antibody, CASP-2 antibody, caspase 2 antibody, caspase-2 antibody, caspase 2 antibody, apoptosis-related cysteine peptidase (neural precursor cell expressed antibody, developmentally down-regulated 2) antibody, caspase 2 antibody, apoptosis-related cysteine protease antibody, caspase-2-like antibody, cysteine protease caspase-2 antibody, ICH1 antibody, ICH-1 antibody, ICH1L1S antibody, ICH-1L/1S antibody, ICH-1 protease antibody, ICH1 protease antibody, Nedd2 antibody, NEDD-2 antibody, neural precursor cell expressed developmentally down-regulated protein 2 antibody, PPP1R57 antibody, protease ICH-1 antibody, protein phosphatase 1 antibody, regulatory subunit 57 antibody, xCaspase-2 antibody
Cross Reactivity Human
Applications ELISA, IHC-P, WB
Immunogen Caspase 2 antibody was raised in Rabbit using a synthetic target peptide as the immunogen

Images

Western Blot analysis using Caspase 2 antibody (20R-2898)

Specifications

Host Rabbit
Isotype IgG
Method of Purification Caspase 2 antibody was purified by Protein A affinity chromatography
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:100, IHC-P: 1:200

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Caspase-2 is an enzyme involved in the programmed cell death process and one of the best-conserved caspases across species. Caspase-2 is unique among caspases in that it has features of both initiator and effector caspases. Two different mRNA species, derived from alternative splicing, encode two proteins, caspase-2L (435 amino acids) and caspase-2S (312 amino acids), which have antagonistic effects on cell death although it is not clear that the shorter form is expressed as a protein. Caspase-2 appears to be necessary for the onset of apoptosis triggered by several insults, including DNA damage, administration of TNF, and different pathogens and viruses.

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Images

  • Western Blot analysis using Caspase 2 antibody (20R-2898) |

Availability: In stock

Price: $295.00
Size: 100 ul
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