Cathepsin H antibody (10R-1021)

Mouse monoclonal Cathepsin H antibody

Synonyms Monoclonal Cathepsin H antibody, Anti-Cathepsin H antibody, ACC-4 antibody, cathepsin H antibody, DkFZp686B24257 antibody, CPSB antibody, ACC-5 antibody, MGC1519 antibody, minichain antibody
Specificity Human
Cross Reactivity To be determined by end-user.
Applications ELISA, WB
Immunogen Cathepsin H antibody was raised in mouse using recombinant human Cathepsin H (23-335 aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone 3G8
Isotype IgG2a kappa
Source Anti-human cathepsin H antibody, clone 3G8, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human cathepsin H protein.
Method of Purification Cathepsin H antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:2,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Cathepsin H is a lysosomal glycoprotein and a member of the cysteine proteinase class. This cysteine protease class comprises cathepsin B, H, k, L, and O. These proteinases are viewed as simple mediators of lysosomal protein degradation. Cathepsin H is synthesized as an inactive proenzyme (41 kDa) and then proteolytically processed to an active single chain, mature form (28 kDa) within the endosomes/lysosomes. This proteinase is a peptidehydrolase that was first isolated from rat liver, and then identified in liver, kidney, spleen, and brain of different mammals. Furthermore, cathepsin H is increased in disease states including breast carcinoma, melanoma, gliomas, and colorectal and prostate carcinoma.

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Availability: In stock

Price: $265.00
Size: 100 ul
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