CBN2p antibody (10R-8486)

Mouse monoclonal CBN2p antibody

Synonyms Monoclonal CBN2p antibody, Anti-CBN2p antibody, CPN2 antibody, carboxypeptidase N antibody, polypeptide 2 antibody, ACBP antibody, acyl CoA binding protein antibody, acyl-CoA-binding protein antibody, arginine carboxypeptidase (carboxypeptidase N) antibody, BOS_939 antibody, carboxypeptidase N 83 kDa chain antibody, carboxypeptidase N large subunit antibody, carboxypeptidase N antibody, polypeptide 2 antibody, 83kD antibody, carboxypeptidase N antibody, polypeptide 2 homolog antibody, carboxypeptidase N regulatory subunit antibody, carboxypeptidase N subunit 2 antibody, DBI antibody, diazepam-binding inhibitor antibody, endozepine antibody, EP antibody, RGD1305170 antibody
Cross Reactivity Human
Applications ELISA, WB
Immunogen CBN2p antibody was raised in Mouse using a protein purified from Human plasma as the immunogen

Images

Western Blot analysis using CBN2p antibody (10R-8486)

Specifications

Host Mouse
Clone 36A1
Isotype IgG1 kappa
Method of Purification CBN2p antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1: 2000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance CBN2p is a member of the CPN/E subfamily of ?regulatory? metallo-carboxypeptidases, is a zinc metalloprotease, which cleaves basic amino acids, lysine and arginine, from the carboxy-terminus of biologically active peptides and proteins. CPN is an extracellular glycoprotein synthesized in the liver and secreted into the blood, where it controls the activity of vasoactive peptide hormones, growth factors and cytokines by specifically removing C-terminal basic residues. Human CPN was discovered as an enzyme that inactivates bradykinin by cleaving its carboxy-terminal arginine and was also referred to as kininase I. CPN is a major inactivator of anaphylatoxins C3a, C4a and C5a and also cleaves off C-terminal Lys residues from larger protein substrates, such as the M and B subunits of creatine kinase, released from the heart after myocardial infarction.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Western Blot analysis using CBN2p antibody (10R-8486) |

Availability: In stock

Price: $295.00
Size: 100 ul
OR
Shipping
View Our Distributors