CBR1 antibody (10R-1771)

Mouse Monoclonal CBR1 antibody

Synonyms Monoclonal CBR1 antibody, Anti-CBR1 antibody, CBR 1, CBR antibody, CBR-1, hCBR1 antibody, Prostaglandin 9 ketoreductase antibody, Prostaglandin E(2) 9 reductase antibody, CBR1, Carbonyl reductase [NADPH] 1.CBR 1 antibody, CBR 1 antibody, CRN antibody, CBR-1 antibody, Carbonyl reductase 1 antibody, NADPH dependent carbonyl reductase 1 antibody, SDR21C1 antibody, Carbonyl reductase 1 15 hydroxyprostaglandin dehydrogenase [NADP+] antibody, CBR1 antibody
Specificity Human
Cross Reactivity Human, Mouse
Applications ELISA, WB
Immunogen CBR1 antibody was raised in mouse using recombinant human CBR1 (1-277 aa ) purified from E. coli

Images

Western Blot analysis of CBR1 antibody (10R-1771)

The cell lysates (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CBR1 antibody (1:1,000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Specifications

Host Mouse
Clone AT4E12
Isotype IgG2a kappa
Source Anti-human CBR1 antibody, clone 4E12, is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CBR1 protein.
Method of Purification CBR1 antibody was purified by Protein G affinity chromatography
Form & Buffer Supplied as a liquid In PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:1,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Carbonyl reductase 1 (CBR1) is an NADPH-dependent, monomeric, and cytosolic enzyme belonging to a family of short-chain dehydrogenases/reductases. This protein consists of 277 amino acid residues and is widely distributed in human tissues such as liver, epidermis, stomach, small intestine, kidney, neuronal cells, and smooth muscle fiber. CBR1 metabolizes many toxic environmental quinones and pharmacological relevant substrates such as the anticancer drug, doxorubicin. The best substrates of CBR1 are quinones, including ubiquinone-1 and tocophrolquinone (vitamin E).

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Western Blot analysis of CBR1 antibody  (10R-1771) | The cell lysates (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CBR1 antibody (1:1,000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Availability: In stock

Price: $265.00
Size: 100 ul
OR
Shipping
View Our Distributors