CCL11 protein (His tag) (80R-1234)
Purified recombinant Human CCL11 protein
|Synonyms||Small inducible cytokine subfamily A (Cys Cys) member 11 protein, CCL11, Chemokine ligand 11 protein, Eosinophil Chemotactic Protein protein, Chemokine CC Motif Ligand 11 protein, CCL 11, Chemokine C C motif ligand 11 protein, Small inducible cytokine A11 CCL 11 protein, CCL-11 protein, CCL 11 protein, CCL-11, MGC22554 protein, SCYA 11 protein, SCYA11 protein, Small inducible cytokine subfamily A member 11.|
Coomassie Blue stained SDS-PAGE of CCL11 protein (His tag) (80R-1234)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||24-97 amino acids: MGSSHHHHHH SSGLVPRGSH MGPASVPTTC CFNLANRKIP LQRLESYRRI TSGKCPQKAV IFKTKLAKDI CADPKKKWVQ DSMKYLDQKS PTPKP|
|Purity||> 90% pure|
|Molecular Weight||10.6 kDa (95aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol, 1mM DTT and 0.1 M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Endotoxin Levels||< 1.0 EU per ug of protein (determined by LAL method )|
|Biological Significance||CCL11 is a small cytokine belonging to the CC chemokine family that is also known as eotaxin-1. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which CCL11 is a ligand include CCR2, CCR3 and CCR5. Recombinant CCL11 protein was expressed in E. coli and purified by using conventional chromatography techniques|
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