CCL28 protein (His tag) (80R-1194)
Purified recombinant Human CCL28 protein
|Synonyms||CCL 28, small inducible cytokine subfamily A (Cys-Cys) member 28 protein, Chemokine (C-C motif) ligand 28 protein, CCL-28, SCYA28 protein, CCL-28 protein, CCL 28 protein, CCL28, CCK1 protein, mucosae-associated epithelial chemokine protein, CC chemokine CCL28 protein, CCL28 protein, small inducible cytokine A28 protein, , MEC protein|
Coomassie Blue stained SDS-PAGE of CCL28 protein (His tag) (80R-1194)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||23-127 amino acids: MGSSHHHHHH SSGLVPRGSH MILPIASSCC TEVSHHISRR LLERVNMCRI QRADGDCDLA AVILHVKRRR ICVSPHNHTV KQWMKVQAAK KNGKGNVCHR KKHHGKRNSN RAHQGKHETY GHKTPY|
|Purity||> 90% pure|
|Molecular Weight||14.3 kDa (126aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 10mM sodium citrate, pH 3.5, containing 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Endotoxin Levels||< 1.0 EU per ug of protein (determined by LAL method)|
|Biological Significance||CCL28, also known as chemokine (C-C motif) ligand 28 or mucosae-associated epithelial chemokine(MEC), belongs to the subfamily of small cytokine CC proteins. CCL28 is expressed by columnar epithelial cells in the gut, lung, breast and the salivary glands and drives the mucosal homing of T and B lymphocytes that express CCR10, and the migration of eosinophils expressing CCR3. This chemokine is constitutively expressed in the colon, but its levels can be increased by pro-inflammatory cytokines and certain bacterial products implying a role in effector cell recruitment to sites of epithelial injury. Recombinant CCL28 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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