CCL5 protein (His tag) (80R-3347)

Purified recombinant CCL5 protein (His tag)

Synonyms EoCP protein, Eosinophil chemotactic cytokine protein, SIS delta protein, Small inducible cytokine A5 protein, T cell specific P228 protein, TCP228 protein, T cell specific RANTES protein, C C motif chemokine 5 protein
Species Human
Protein Type Recombinant
Applications ELISA, SDS-PAGE, WB

Images

SDS-PAGE analysis of CCL5 protein (His tag) (80R-3347)

Specifications

Expression System E.coli
Purity > 90% pure
Molecular Weight 14 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-Hcl, 0.5MNaCl, 10% glycerin (pH 8.0) and 200 mM Imidazole

Storage & Safety

Storage Store at 4 deg C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 deg C, avoid repeat freeze/thaw cycles

General Information

Biological Significance CCL5 is a chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. Binds to CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils. 0 1 2.

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Images

  • SDS-PAGE analysis of CCL5 protein (His tag) (80R-3347)

Availability: In stock

Price: $210.00
Size: 50 ug
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