CCND1 Blocking Peptide (33R-1076)

A synthetic peptide for use as a blocking control in assays to test for specificity of CCND1 antibody, catalog no. 70R-10480

Synonyms CCND1 control peptide, CCND1 antibody Blocking Peptide, Anti-CCND1 Blocking Peptide, cyclin D1 Blocking Peptide, BCL1 Blocking Peptide, D11S287E Blocking Peptide, PRAD1 Blocking Peptide, U21B31 Blocking Peptide, CCND1, CCND-1, CCND 1, CCND-1 Blocking Peptide, CCND 1 Blocking Peptide
Protein Type Synthetic
Applications IHC, WB


Molecular Weight 34 kDa
Form & Buffer Lyophilized powder. Add 100ul of distilled water for a final peptide concentration is 1 mg/ml.

Storage & Safety

Storage Store at -20 deg C long term. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance CCND1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.

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Availability: In stock

Price: $130.00
Size: 100 ug
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