CCND3 antibody (70R-10481)

Affinity purified rabbit polyclonal CCND3 antibody

Synonyms Polyclonal CCND3 antibody, Anti-CCND3 antibody, CCND-3 antibody, CCND-3, CCND 3 antibody, CCND 3, CCND3, cyclin D3 antibody
Cross Reactivity Human, Mouse, Rat, Dog, Bovine, Pig, Chicken
Applications IHC, WB
Immunogen CCND3 antibody was raised in rabbit using the C terminal of CCND3 as the immunogen
Assay Information CCND3 Blocking Peptide, catalog no. 33R-1779, is also available for use as a blocking control in assays to test for specificity of this CCND3 antibody

Images

Immunohistochemical staining using CCND3 antibody (70R-10481)

Human Muscle

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance CCND3 encodes a protein that belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.

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Images

  • Immunohistochemical staining using CCND3 antibody (70R-10481) | Human Muscle
  • Western blot analysis using CCND3 antibody (70R-10481) | Recommended CCND3 Antibody Titration: 0.2-1 ug/ml

Availability: In stock

Price: $345.00
Size: 50 ug
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