CCNF antibody (10R-1363)

Mouse monoclonal CCNF antibody

Synonyms Monoclonal CCNF antibody, Anti-CCNF antibody, FBXO1 antibody, Cyclin F antibody, FBX1 antibody
Specificity Human CCNF
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen CCNF antibody was raised in mouse using recombinant Human Cyclin F (Ccnf)

Images

Western Blot analysis of immunized recombinant protein using CCNF antibody (10R-1363)

Specifications

Host Mouse
Clone 2123D1a
Isotype IgG1
Method of Purification CCNF antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer CCNF antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified.

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Images

  • Western Blot analysis of immunized recombinant protein using CCNF antibody (10R-1363)

Availability: In stock

Price: $190.00
Size: 50 ug
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