CD11a antibody (10R-CD11aaMS)

Rat monoclonal CD11a antibody

Synonyms Monoclonal CD11a antibody, Anti-CD11a antibody, CD-11a, CD 11a, CD 11a antibody, CD-11a antibody, CD11a, LFA1a antibody
Specificity Murine CD11a
Cross Reactivity To be determined by end-user
Applications FC, IHC, IP
Immunogen CD11a antibody was raised in rat using murine CD11a (LFA-a1) as the immunogen.

Specifications

Host Rat
Clone I21/7
Isotype IgG2a
Form & Buffer Supplied as a liquid in 100mM BBS, pH 8.2.
Concentration 0.5 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.

General Information

Biological Significance Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a human gene which functions in the immune system. It is involved in cellular adhesion and costimulatory signaling. It is the target of the drug efalizumab. ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling.

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Availability: In stock

Price: $315.00
Size: 500 ug
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