CD11a antibody (Azide Free) (10R-CD11aaMSp)

Rat monoclonal CD11a antibody (Azide Free)

Synonyms Monoclonal CD11a antibody, Anti-CD11a antibody, CD-11a, CD11a, CD 11a, CD-11a antibody, CD 11a antibody, LFA1a antibody
Specificity Murine CD11a
Cross Reactivity To be determined by end-user
Applications FC, IHC, IP, WB
Immunogen CD11a antibody (Azide Free) was raised in rat using murine CD11a (LFA-1a) as the immunogen.

Specifications

Host Rat
Clone I21/7
Isotype IgG2a
Form & Buffer Supplied as a liquid in PBS.
Concentration 0.5 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles

General Information

Biological Significance Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a human gene which functions in the immune system. It is involved in cellular adhesion and costimulatory signaling. It is the target of the drug efalizumab. ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Availability: In stock

Price: $375.00
Size: 500 ug
OR
Shipping
View Our Distributors