CD18 antibody (PE) (61R-CD18eMSPE)

Rat monoclonal CD18 antibody (PE)

Synonyms Monoclonal CD18 antibody, Anti-CD18 antibody, b2 Integrin antibody, CD-18, beta 2 Integrin antibody, CD18, CD 18 antibody, CD 18, CD-18 antibody
Specificity Murine CD18
Cross Reactivity To be determined by end-user
Applications FC, IHC
Immunogen CD18 antibody (PE) was raised in rat using cell membrane lysates derived from murine T cell lymphoma BW5147 as the immunogen.

Specifications

Host Rat
Clone C71/16
Isotype IgG2a
Tag/Conjugate PE
Form & Buffer Supplied as a liquid in PBS, with NaN3 added as preservative.
Concentration 0.1 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Integrin beta-2 (CD18) is a protein that in humans is encoded by the ITGB2 gene. The ITGB2 protein product is the integrin beta chain beta 2. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. In humans lack of CD18 causes Leukocyte Adhesion Deficiency, a disease defined by a lack of leukocyte extravasation from blood into tissues.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Availability: In stock

Price: $195.00
Size: 100 ug
OR
Shipping
View Our Distributors