CD19 antibody (10R-1794)

Mouse monoclonal CD19 antibody

Synonyms Monoclonal CD19 antibody, Anti-CD19 antibody, B-lymphocyte antigen CD19 antibody, CD 19 antibody, CD19, CD 19, Cluster of Differentiation 19 antibody, CD-19, CD-19 antibody
Cross Reactivity Human
Applications ELISA, IHC, WB
Immunogen CD19 antibody was raised in Mouse using a purified recombinant fragment of human CD19 expressed in E. coli as the immunogen.

Images

Immunohistochemical staining using CD19 antibody (10R-1794)

Immunohistochemical analysis of paraffin-embedded human normal lymph node, showing cytoplasmic localization using CD19 antibody with DAB staining.

Specifications

Host Mouse
Clone 2E2B6B10
Isotype IgG2a
Form & Buffer Purified antibody supplied in PBS containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance CD19 is a protein that in humans is encoded by the CD19 gene. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase.

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Images

  • Immunohistochemical staining using CD19 antibody (10R-1794) | Immunohistochemical analysis of paraffin-embedded human normal lymph node, showing cytoplasmic localization using CD19 antibody with DAB staining.
  • Western Blot analysis using CD19 antibody (10R-1794) | Western Blot showing CD19 antibody used against CD19 recombinant protein.

Availability: In stock

Price: $195.00
Size: 100 ul
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