CD22 antibody (10R-CD22cMS)

Rat monoclonal CD22 antibody

Synonyms Monoclonal CD22 antibody, Anti-CD22 antibody, CD-22 antibody, CD 22, CD 22 antibody, CD-22, FceRII antibody, CD22
Specificity Murine
Cross Reactivity To be determined by end-user
Applications FC, IP
Immunogen CD22 antibody was raised in rat using CD22 as the immunogen.

Specifications

Host Rat
Clone 2D6
Isotype IgG1
Form & Buffer Supplied as a liquid in 100mM BBS, pH 8.2.
Concentration 0.5 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.

General Information

Biological Significance CD22 or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking, CD22 is a regulatory molecule that prevents the overactivation of the immune system and the development of autoimmune diseases. CD22 is a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. The presence of Ig domains makes CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signalling.

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Availability: In stock

Price: $395.00
Size: 500 ug
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