CD226 protein (His tag) (80R-2658)
Purified recombinant Human CD226 protein (His tag)
|Synonyms||PTA1 protein, CD 226 protein, CD-226 protein, DNAM 1 protein, CD-226 protein, CD226 protein, CD 226 protein, CD226 antigen protein, CD-226, TLiSA1 protein, CD 226, Cluster of Differentiation 226 DNAM-1 protein, CD226, DNAM-1 protein, DNAM1 protein|
SDS-PAGE analysis of CD226 protein (His tag) (80R-2658)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||19-254 aa: MGSSHHHHHH SSGLVPRGSH MGSEEVLWHT SVPFAENMSL ECVYPSMGIL TQVEWFKIGT QQDSIAIFSP THGMVIRKPY AERVYFLNST MASNNMTLFF RNASEDDVGY YSCSLYTYPQ GTWQKVIQVV QSDSFEAAVP SNSHIVSEPG KNVTLTCQPQ MTWPVQAVRW EKIQPRQIDL LTYCNLVHGR NFTSKFPRQI VSNCSHGRWS VIVIPDVTVS DSGLYRCYLQ ASAGENETFV MRLTVAEGKT DNQYTLFVA|
|Method of Purification||CD226 protein was purified using Protein G affinity chromatography|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||CD226 is a 65kDa glycoprotein expressed on the surface NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. This protein also plays a role in megakaryocytic cell maturation. Recombinant human CD226 protein, fused to His-tag at N-terminus, was expressed in E.coli.|
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