CD27 antibody (10R-7982)

Armenian Hamster monoclonal CD27 antibody

Synonyms Monoclonal CD27 antibody, Anti-CD27 antibody, TNFRSF7 antibody, T14 antibody, CD 27 antibody, CD-27 antibody, CD 27, CD-27, CD27
Cross Reactivity Human, Mouse
Applications ELISA, FC, IHC-F, IHC-P, IP
Immunogen CD27 antibody was raised in Armenian Hamster using Human CD27 as the immunogen.

Specifications

Host Hamster
Clone LG.3A10
Isotype IgG
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations Optimal dilution should be determined by titration

General Information

Biological Significance The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

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Availability: In stock

Price: $425.00
Size: 100 ug
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