CD274 protein (His tag) (80R-2283)
Purified recombinant Human CD274 Protein (His tag)
|Synonyms||B7-H protein, PDL1 protein, PD-L1 protein, CD-274, B7H1 protein, CD274, CD 274 protein, CD 274, CD-274 protein, PDCD1LG1 protein, PDCD1L1 protein|
Coomassie Blue stained SDS-PAGE of CD274 protein (His tag) (80R-2283)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||MGSSHHHHHH SSGLVPRGSH MGSHMFTVTV PKDLYVVEYG SNMTIECKFP VEKQLDLAAL IVYWEMEDKN IIQFVHGEED LKVQHSSYRQ RARLLKDQLS LGNAALQITD VKLQDAGVYR CMISYGGADY KRITVKVNAP YNKINQRILV VDPVTSEHEL TCQAEGYPKA EVIWTSSDHQ VLSGKTTTTN SKREEKLFNV TSTLRINTTT NEIFYCTFRR LDPEENHTAE LVIPELPLAH PPNER|
|Purity||> 90% pure|
|Molecular Weight||27.9 kDa|
|Form & Buffer||Supplied in liquid form in 20 mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT|
Storage & Safety
|Storage||Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.|
|Biological Significance||CD274, also known as programmed cell death 1 ligand 1, is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. This protein interaction with PDCD1 inhibits T-cell proliferation and cytokine production. Recombinant human CD274 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.|
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