CD3 antibody (10R-1790)
Mouse monoclonal CD3 antibody
|Synonyms||Monoclonal CD3 antibody, Anti-CD3 antibody, Cluster of differentiation 3 antibody, CD-3 antibody, CD-3, CD3, CD 3 antibody, CD 3|
|Applications||ELISA, FC, WB|
|Immunogen||CD3 antibody was raised in Mouse using a purified recombinant fragment of human CD3 expressed in E. coli as the immunogen.|
Flow Cytometric assay using (CD3 antibody)
FC analysis CD3 expressed in human peripheral blood cells.
|Form & Buffer||Supplied lyophilized from a 0.2 um filtered solution in PBS.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, FC: 1:200-1:400, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||In immunology, the CD3 T-Cell Co-Receptor is a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3 Delta chain and two CD3 Epsilon chains. These chains associate with a molecule known as the T cell receptor (TCR) and the Zeta-chain to generate an activation signal in T lymphocytes. The TCR, Zeta-chain and CD3 molecules together comprise the TCR complex.|
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