CD40 antibody (10R-1815)
Mouse monoclonal CD40 antibody
|Synonyms||Monoclonal CD40 antibody, Anti-CD40 antibody, gp39 antibody, CD-40 antibody, TNFSF5 antibody, TRAP antibody, Soluble CD40 Ligand antibody, CD-40, CD40, Cluster of differentiation 40 antibody, CD 40, T-BAM antibody, CD154 antibody, CD 40 antibody|
|Immunogen||CD40 antibody was raised in Mouse using a purified recombinant fragment of CD40 expressed in E. coli as the immunogen.|
Immunofluorescent staining using (CD40 antibody)
Confocal immunofluorescence analysis of human peripheral blood lymphocyles (left) and mouse L1210 cells (right) using CD40 antibody (green). Blue: DRAQ5 fluorescent DNA dye.
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, IF: 1:200-1:1000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. Deficiency can cause Hyper-IgM syndrome type 3.|
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