CD44 antibody (10R-CD44aHU)

Rat monoclonal CD44 antibody

Synonyms Monoclonal CD44 antibody, Anti-CD44 antibody, CD44, Pgp1 antibody, CD 44 antibody, CD 44, H-CAM antibody, HCAM antibody, CD-44, CD-44 antibody, chondroitin sulfate proteoglycan 8 antibody, MDU2 antibody, CSPG8 antibody, IN antibody, CD-44 antibody, CD44R antibody, MDU3 antibody, hematopoietic cell E- and L-selectin ligand antibody
Specificity Human CD44
Cross Reactivity To be determined by end-user
Applications FC, IHC, IP, Neutralization
Immunogen CD44 antibody was raised in rat using H-CAM (CD44) as the immunogen.

Images

Flow Cytometric assay using CD44 antibody (10R-CD44aHU)

Flow Cytometric assay showing Beta 1 integrin and CD44 surface expression on MV3 melanoma cells incorporated into 3-D collagen lattices using CD14 antibody (10R-CD44aHU)

Specifications

Host Rat
Clone HERMES-1
Isotype IgG2a
Form & Buffer Purified IgG supplied as a liquid in PBS.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles

General Information

Biological Significance CD44 is a receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes.

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Images

  • Flow Cytometric assay using CD44 antibody (10R-CD44aHU) | Flow Cytometric assay showing Beta 1 integrin and CD44 surface expression on MV3 melanoma cells incorporated into 3-D collagen lattices using CD14 antibody (10R-CD44aHU)

Availability: In stock

Price: $593.25
Size: 200 ug
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