CD49e antibody (10R-8079)

Mouse monoclonal CD49e antibody

Synonyms Monoclonal CD49e antibody, Anti-CD49e antibody, CD 49e antibody, CD-49e antibody, CD 49, CD-49, CD49
Specificity Recognizes the 135-kDa integrin-alpha5 monocyte-specific antigen. The exact epitope is not known NKI-SAM-1 strongly reacts with monocytes, and weakly with granulocytes, platelets and T-lymphocytes
Cross Reactivity Human
Applications FC, IHC-F, IP
Immunogen CD49e antibody was raised in Mouse using human monocytes isolated by centrifugal elutriation as the immunogen.

Specifications

Host Mouse
Clone NKI-SAM-1
Isotype IgG2b
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations Optimal dilution should be determined by titration

General Information

Biological Significance CD49e is a member of the integrin alpha chain family, and binds with CD29 (integrin Beta1) to form the receptor VLA5, which binds the ligands fibronectin and fibrinogen. CD49e is a type I, single-pass membrane protein, with a molecular weight of 135 kDa, and is expressed on multiple cell types including thymocytes, mast cells, activated T cells and splenic B cells. In addition to its role in adhesion, VLA5 contributes to T-cell co-stimulation.

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Availability: In stock

Price: $425.00
Size: 100 ug
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