CD49e antibody (10R-CD49EART)
Hamster monoclonal CD49e antibody
|Synonyms||Monoclonal CD49e antibody, Anti-CD49e antibody, CD 49e antibody, CD-49e, CD49e, CD-49e antibody, CD 49e|
|Cross Reactivity||Mouse, rat|
|Immunogen||CD49E antibody was raised in hamster using mouse/rat CD49 as the immunogen.|
Flow Cytometric analysis using CD49e antibody (10R-CD49EART)
Staining of C57Bl/6 bone marrow cells with 0.5 ug of Armenian Hamster IgG Isotype Control (left) or 0.5 ug of CD49e antibody (right) followed by Anti-Armenian Hamster IgG (FITC). Total viable cells were used for analysis.
|Form & Buffer||PBS, pH 7.2, with 0.09% NaN3.|
Usage & Assay Information
|Usage Recommendations||FC: 1 ug/test|
Storage & Safety
|Storage||Store at 4 deg C.|
|Biohazard Information||This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.|
|Biological Significance||CD49e is a member of the integrin alpha chain family, and binds with CD29 (integrin Beta1) to form the receptor VLA?5, which binds the ligands fibronectin and fibrinogen. CD49e is a type I, single?pass membrane protein, with a molecular weight of 135 kDa, and is expressed on multiple cell types including thymocytes, mast cells, activated T cells and splenic B cells. In addition to its role in adhesion, VLA?5 contributes to T?cell co?stimulation.|
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