CD49f antibody (10R-8077)

Rat monoclonal CD49f antibody

Synonyms Monoclonal CD49f antibody, Anti-CD49f antibody, Integrin a6 antibody, ITGA6 antibody, VLA6 antibody, CD 49f antibody, CD-49f antibody, CD 49f, CD-49f, CD49f
Cross Reactivity Human, Mouse
Applications FC, IHC-F, IP
Immunogen CD49f antibody was raised in Rat using mouse (Balb/c) mammary tumor cells as the immunogen.


Host Rat
Clone NKI-GoH3
Isotype IgG2a
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations Optimal dilution should be determined by titration

General Information

Biological Significance CD49f is a 120 kD transmembrane protein. CD49f associates with CD29, the integrin beta 1 chain, to form the VLA-6 complex CD49f also associates with CD104, the integrin beta 4 chain, to form the alpha 6 beta 4 complex. CD49f is expressed primarily on T cells, monocytes, platelets, epithelial and endothelial cells. CD49f expression has also been found on germinal center B cells. The GoH3 antibody is cross-reactive to integrin alpha 6 on human, mouse and bovine cells. This antibody has also been reported to have functional activity in blocking the binding of integrin alpha 6 to laminin.

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Availability: In stock

Price: $345.00
Size: 100 ug
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