CD5 antibody (10-Z05A)

Mouse monoclonal CD5 antibody

Synonyms Monoclonal CD5 antibody, Anti-CD5 antibody, CD 5 antibody, CD-5, CD5, CD-5 antibody, CD 5
Specificity Human
Cross Reactivity To be determined by end-user
Applications User optimized
Immunogen CD5 antibody was raised in mouse using human blood lymphocytes as the immunogen.

Specifications

Host Mouse
Clone M504507
Isotype IgG1
Method of Purification CD5 antibody was purified by chromatography on protein A Sepharose.
Form & Buffer Purified from murine ascites by column chromatography and supplied in PBS, pH 7.5, with 0.08% NaN3.
Concentration Batch dependent - please inquire should you have specific requirements

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins. CD5 was used as a T-cell marker until monoclonal antibodies against CD3 were developed. In humans, the CD5 gene is located on the long arm of chromosome 11.

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Availability: In stock

Price: $95.00
Size: 200 ug
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