CD5 antibody (FITC) (61R-CD5cMSFTx)

Rat monoclonal CD5 antibody (FITC)

Synonyms Monoclonal CD5 antibody, Anti-CD5 antibody, CD-5, CD 5, CD-5 antibody, Ly1 antibody, CD5, CD 5 antibody
Specificity Murine
Applications FC
Immunogen CD5 antibody (FITC) was raised in rat using CD5/Lyt-1 as the immunogen.

Specifications

Host Rat
Clone B19.1
Isotype IgG2a
Tag/Conjugate FITC
Form & Buffer Supplied as a liquid in PBS, with NaN3 added as preservative.
Concentration 0.1 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins. CD5 was used as a T-cell marker until monoclonal antibodies against CD3 were developed. In humans, the gene is located on the long arm of chromosome 11. There is no confimed ligand for CD5.

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Availability: In stock

Price: $125.00
Size: 100 ug
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