CD56 antibody (10R-8094)

Mouse monoclonal CD56 antibody

Synonyms Monoclonal CD56 antibody, Anti-CD56 antibody, LFA3 antibody, CD56
Specificity Recognizes NCAM which is present in small cell lung cancer (SCLC) and lung carcinoids
Cross Reactivity Human, Mouse
Applications IHC, IHC-F
Immunogen CD56 antibody was raised in Mouse using the small cell lung cancer cell line NCI-H82 as the immunogen.

Specifications

Host Mouse
Clone RNL-1
Isotype IgG1
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations IHC: 1:100-1:200

General Information

Biological Significance CD56, an isoform of the neural cell adhesion molecule (NCAM), is a 220 kDa heavily glycosylated type I transmembrane protein. On human hematopoietic cells, its expression is restricted to NK cells and a subpopulation of T lymphocytes (known as large granular lymphocytes) which demonstrate natural killer activity. While it is clear that NCAM plays a role in homotypic adhesion of neuronal cells, the significance of CD56 expression on NK cells is not clear and remains controversial.

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Availability: In stock

Price: $375.00
Size: 100 ug
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